1 Marlowe: {approaching Will's desk} Shakespeare, office B down on level 2 has become free. You're next in line.
2 Shakespeare: Thanks, Mr Marlowe, but isn't that the one near the photocopier? That's always really noisy?
3 Marlowe: Look, do you want it or not?
4 [caption]: This punchline blocked by PunGuard 2.1. Your best protection against hackneyed wordplay. Now with ClichéStopper.

Yeah, it was an obvious punchline. Gimme a break, it's hard writing original stuff every day. At least there isn't some sort of automatic bad pun detector software that can censor my jokes.

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Well, okay, it's obvious if you are familiar with the famous soliloquy from Hamlet, and figure out that office B on level 2 is office "2B". That should be enough hints for anyone. :-)

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2014-12-01 Rerun commentary: When this comic originally ran, it didn't have the second part of the annotation above, and I got several people writing to ask what this "obvious" punchline was, so I had to provide a hint.

I'm not sure why - it's right there in the comic, in the dialogue of the last panel.