1 Charon: I'm taking you to the River Mnemosyne.
1 Adam: What's that?
2 Charon: The waters of the Mnemosyne will restore your memories.
2 Jamie: What's a memory?
2 Adam: What's water?
3 Charon: Oh for crying out loud!
4 Jamie: Well, I don't need to ask what that is. I get it from the tone of voice.

There's surprisingly little information on the River Mnemosyne on the web. I'd have thought there'd be more for a classical subject like this.

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2019-02-17 Rerun commentary: Especially one that is supposed to give you memories.

But with the passing of ten years of people putting more stuff on the Internet since this comic was originally published, there are now several places where you can learn more about the river Mnemosyne.