1 Man: Mr Newton, I've come to ask you an important question regarding your specialised fields of knowledge.
1 Isaac Newton: Go on.
2 Man: As an expert in the effects of alcohol and of mixing various elixirs and tonics...
3 Man: What is the best thing for a hangover?
4 Isaac Newton: Easy. Drink heavily the night before.

It's bound to be an old joke, but I stumbled across it for the first time the other day, and was so taken by it that I had to spread it further.

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2022-06-12 Rerun commentary: It's not known for certain if Newtown had much to do with alcohol, but given that water was a generally unsafe drink at the time and there weren't many other options, most people imbibed alcohol.

Given his propensity to experiment on himself, I like to think that Newton had some rollicking good drunken times.